Blogs

Follow the copper in this index of blogs over the past 14 months as we posted old thoughts and explored new ones as Cu(I)NA2 as an acute Covid-19 treatment and as a Long Covid treatment. Long Covid symptoms resemble those of many current CopperOne customers.

• July 7^th 2021 This post goes even further into the literature on the GSQ-30 and Chronic Lyme Disease and Long Covid symptoms. Somewhere along the way it was discovered that copper deficiency symptoms overlap GSQ-30 symptoms.
• July 2^nd 2021 The GSQ-30 was written for PTLD whose symptoms overlap Long Covid. The reference cited found some interesting ways of clustering the answers into groups for PTLD.
• June 23^rd 2021 This post presents the latest somewhat conflicting data on serum copper in patients with severe active Covid-19 infections. Failure to absorb and loss in the urine are discussed.
• June 18^th 2021 Data supporting actin auto antibodies in Long Covid are presented.
• June 5^th 2021 We came across the work of Daniel Amen. Dr Amen is a pioneer in the use of single-photon emission computerized tomography (SPECT) as a tool in psychiatry and neuro degenerative diseases like Alzheimer’s Disease. Dr Amen sells brain directed nutrients that include Cu²⁺ and niacin.
• June 3^rd 2021 The SF-36 questionnaire has been used to assess chronic fatigue syndrome, PTLD, and now Long Covid. This post is being presented so that potential participants and CopperOne customers can tell us if these questions speak to them.
• June 2^nd 2021 There are those who think that Long Covid is an autonomic nervous system disease. This post is an ANS questionnaire is waiting for comment of anyone who wants to give it.
• May 29^th 2021 This post compares Post Treatment Lyme Disease with Long Covid and what it might mean for CopperOne. It is password protected for now.
• May 20^th 2021 This post is inresponse to a survivorscorps webinar in which the idea was floated that vasculitis is part of Long Covid. Is there an autoimmune possibility? This post reviews some interesting speculation in the literature.
• May 17^th 2021 This site reviews some clinical trials for treating Long Covid and some of our ideas. This one is password protected for now.
• May 12^th 2021 This post explores the mechanisms of red light therapy and the potential enhancement with copper,
• May 10^th 2021 A colleague published some encouraging results of the autoimmune protocol diet in patients with and autoimmune disease. Part of this diet includes copper and niacin rich organ meats.
• May 4^th 2021 This post reviews some papers suggesting interaction of Covid-19 proteins with mitochondrial proteins. We don’t know much what it means.
• April 26^th 2021 Long Covid is starting to looklike an autoimmune disease. There are some reports of NMDA receptor autoantibodies. This post critically considers what all of this might mean.
• April 20^th 2021 This post follows a request for information from some farmers who were not getting optimal milk from their cows. As it turns out it is quite common to supplement cows with copper and/or niacin. CopperOne would be the first two in one supplement. This post discusses the role of copper and niacin in milk production.
• April 12^th 2021 Niacin is a precursor of NADH/NAD⁺ of the electron transport chain. We review papers that discuss the role of NAD⁺ in numerous metabolic pathways that include the longevity sirtuin enzymes.
• April 9^th 2021 Multiple sources say that copper supplementation enhances vaccines.
• April 4^th 2021 This post describes Coivd-19 variants of concern back in April. The D614G variant is particularly interesting in that it could help the virus become a chronic infection. Maybe.
• March 30^th 2021 This post describes outcome measures we had planned for acute Covid-19 infections and whether they would apply to Long Covid. This post is password protected.
• March 25^th 2021 Postural orthostatic tachycardia syndrome POTS is observed in Long Covid. This post describes the locus ceruleus, dopamine beta hydrolase and a brilliant study by Henk Lukaski on mean arterial blood pressure in copper deficient young female humans.
• March 18^th 2021 A CopperOne customer asked if Cu(I)NA₂ would alleviate ALS symptoms if CuASM alleviates ALS symptoms. The password protected answer is we do not know.
• March 5^th 2021 This post compares symptoms of Long Covid with acute Covid infections.
• February 1^st 2021 This post goes into great detail as to how we analyzed neutrophil to lymphocyte data in our Phase 1 clinical trial.
• January 25^th 2021 As a nutraceutical company we use color as a quality control of Cu(I)NA₂. This requires a trained eye. This post describes some thoughts on making hte process more reproducible.
• January 19^th 2021 This post describes how two different formulations of Cu²⁺ were used to enhance the immune response of broiler chickens. Implications of Cu⁺ vs Cu²⁺ in Covid and Long Covid are presented.
• October 16^th 2020 This post is about copper in fungal isoforms of copper super oxide dismutases. This post contains a dog with Valley Fever story that would not be interpreted as medical advice.
• July 19^th 2020 This post was created for CopperOne customers who claim benefit to record their symptoms. Then it got turned into a post for Long Covid citizen scientists to record their symptoms.
• July 19^th 2020 This post covers the dual role of copper in the interleukin-1 producing inflammasome in turning it on and mitigating resulting oxidative stress.
• July 16^th 2020 This post covers the role of the locus ceruleus in ventilation.
• July 14^th 2020 This is a fun post that shows how physicians monitored fevers hundreds of years ago.
• July 3^rd 2020 We were getting some reports that Coivd-19 patients were seeing their fevers reduced by Cu(I)NA₂. This post discusses studies that show that Paracetamol can reduce fevers.
• May 28^th 2020. This is about copper chaperones with emphasis on the Cu⁺ part.
• May 27^th 2020 This post is a discussion of the Cu⁺ transporter Ctr1.
• May 26^th 2020 This post is simply an introduction to the copper carrier ceruloplasmin.
• May 26^th 2020 This post describes how gastric bypass patients may become copper deficient and may need additional copper for eye health.
• May 25^th 2020 This post describes the use of Cu(I)NA₂ to treat a rodent model of fatty liver disease. The investigators did not use a standard Cu(II) supplement so we do not know if the beneficial effects were unique to Cu(I).
• May 22^nd 2020 This post is simply a discussion of minerals important for bone health.
• May 20^th 2020 This post is a letter of support from Dr George Brewer MD for CopperOne. Dr Brewer is an MD scientist who was one of the first to report the connection to Cu2+ in pipes and Alzheimer’s Disease.
• May 19th 2020 The blog addresses the fear that any oxidative state of copper can contribute to Alzheimer’s Disease. An observation that seniors may have less Cu/Zn SOD activity in their lungs. Is copper safe for seniors? DO NOT use this post as medical advice but rather discuss this post with your physician!
• May 19th 2020 This blog is about niacin in immune function.
• May 18th 2020 This post covers the role of copper in the renin angtioensin system. The RAS is active in bacterial and fungal infections, not just Covid-19. It sort of explores the potential of Cu(I)NA₂ as a medical food is examined. It will remain password protected for now.
• May 18th 2020 This post reviews some fish studies showing that Cu(I)NA₂ improves the immune response to vaccines against a bacterial fish pathogen. Read this post with the caveat that the US FDA does not recognize studies performed in fish.
• May 18^th 2020 This post reviews the importance of copper in both neutrophils and lympohocytes in the neutrophil to lymphocyte ratio that were a big thing when the Covid-19 pandemic was in full force. NET proteins are reactive oxygen species are also discussed.
• May 15^th 2020. This one is still password protected for now. A CopperOne customer sent the CEO a news clip that suggested something negative about Copper in the +1 oxidation state. This post explains some extremely complicated science in lay terms.
• May 14^th 2020 This post was created to refute some crazy Covid-19 treatments that might contain CopperOne.
• May 12th 2020 we came up with the idea that mycoplasma infections could make Covid-19 infections worse. Further research is proving us correct. We probably still need to test the ability of Cu(I)NA2 to kill these bacteria that lack cell walls.

Copper is important in maintaining blood flow to muscles. This is a story of Cu/Zn SOD 1/3 and reactive oxygen species from NADPH oxidase.

You can enjoy some details of our clinical trial on a post about the Revised Symptom Impact Questionnaire, SIQR. This questionnaire was written for fibromyalgia patients. We had to separate the male and female participants to address some of the gender bias nature of the questions.